Good HDL Cholesterol and risk factor


High HDL Cholesterol count in your body is a good thing, as HDL Cholesterol is functionally a good Cholesterol. As a proportional measure about One-fourth to one-third of blood cholesterol is carried by HDL.  HDL cholesterol is considered “good” cholesterol ,as it helps remove LDL cholesterol from the arteries through reverse cholesterol transport. HDL is able to act as a mop as it mitigates LDL cholesterol away from the arteries, back to the liver; where it is broken down and passed out from the body.

 The average ratio of LDL to HDL in body is 3-to-1 ratio. Cholesterol levels are measured in milligrams (mg) of cholesterol per deciliter (dL) of blood or millimoles (mmol) per liter (L) in 8 to 12 hours fasting condition. A total cholesterol score of less than 180 mg/dL is optimal for body physiology and functioning. Its desirable to have HDL-C measure greater than 60mg/dL (1.6mmol/dL) for men and HDL-C count less than Less than 40 mg/dL (1.0 mmol/L) is men is considered at risk. Similarly,  HDL-C measure greater than 60mg/dL (1.6mmol/dL) is optimum in females and HDL-C count less than Less than 50 mg/dL (1.3 mmol/L) is female fraternity is considered at risk.

HDL-C is able to drive a process called “Reverse Cholesterol Transport”. HDL-C binds to the excess cholesterol deposited on the inner walls of blood vessels and anchors it back to liver for elimination through GI track. This keeps the blood vessels dilated, promoting better blood flow.  HDL Cholesterol lower inflammation and is clued to be a potential help to the body’s immune system against Alzheimer’s disease. Additionally, anti-oxidant (inhibits the oxidation of other molecules by preventing transfer of electrons or hydrogen atom)and anti-inflammatory properties(reducing inflammation or reducing swelling) of HDL-C reduce occurrences of injury in blood vessels. The risk of atherosclerotic disease is documented to be  inversely proportional to the blood levels of HDL-C, that means the higher your HDL, the lower your risk. Inversely, HDL-C levels less than 1 mg/dL of blood, increases the risk of atherosclerotic disease. Studies show that 1-mg/dL rise in HDL-C in your lipid profile, decreases the risk for developing cardiovascular disease decreases by 2% to 3%.

Lifestyle discrepancies such as obesity, cigarette smoking and sedentary life style reduce the blood levels of HDL-C. Lifestyle modification is always frontline therapy in improving HDL-Cholesterol levels in your body. After losing weight chances are that there is an elevation in your HDL-C levels. The more you exercise, greater is the gain in HDL-C levels. Quitting smoking provides a prompt 15 to 20% increase in HDL-C levels in your body. A balanced diet comprising of fish, reduced carbohydrate consumption, fruits, vegetables, whole grains,  olive oil and legumes are known to boost HDL-C levels. Mutation and gene variations have added higher HDL-C levels down the heredity from parents to the off-springs.



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